Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood circulate in males with established coronary artery illness . Therefore, an interplay of endogenous components of the patient’s risk profile as well as the testosterone dosing could additionally be issues of whether or not opposed occasions occur. Erythrocytosis has been reported as a potential effect of testosterone, which can be beneficial in sufferers with anemia. The biggest threat of erythrocytosis occurs with injectable forms of testosterone in contrast with transdermal preparations, particularly in supraphysiologic doses. An increase of up to 44% of the baseline hematocrit has been reported . Moreover, testosterone has been used within the remedy of decreased muscle mass and bone density in addition to anemia. The position testosterone may play in the development of cardiovascular disease has increasingly turn into the topic of present interest .
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- Relationship between endogenous intercourse hormone levels, lipoproteins and coronary atherosclerosis in males present process coronary angiography.
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Relationship between endogenous sex hormone levels, lipoproteins and coronary atherosclerosis in males present process coronary angiography. Basaria S, Dobs AS. Risks versus advantages of testosterone therapy in elderly men. Scientific and technological companies cam sod and research and design relating thereto; industrial analysis and analysis providers; design and growth of pc hardware and software program.
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with conventional cardiac threat factors utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person also had polycythemia, probably secondary to high-dose testosterone. The affected person underwent successful percutaneous intervention of the best coronary artery. Physicians and patients ought to be conscious of the scientific penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a element of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity. However, testosterone in physiologic doses could even be beneficial in patients with angina , have greater ischemic thresholds and improved quality of life .
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